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br Case report A year old man was diagnosed with
2019-06-24
Case report A 73 year-old man was diagnosed with chronic lymphocytic lymphoma (CLL) in December 2009, where he presented with a servical mass at another state hospital. He was treated with 6 cycles of cyclophosphamide, vincristine and prednisone (CVP). On follow-up he received 6 cycles of fludara
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Declaration of interests br Abstract Background In times of
2019-06-24
Declaration of interests Abstract Background In times of seawater inundation in coastal deltas, unprotected drinking water sources, such as ponds and shallow tube wells, take on salt water with each inundation. Daily consumption of these saline sources contributes to overall sodium intake. Altho
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Analyses such as those used by Burke and colleagues rely
2019-06-24
Analyses such as those used by Burke and colleagues rely on periodic cross-sectional surveys that are not linked to available or civic registration and vital statistics databases. These surveys are also limited by the inevitable time lag between analyses and feedback to health systems and policy mak
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The predicted mean time to
2019-06-24
The predicted mean time to attaining the maximal indirect impact is relevant when considering adult vaccination with PCV. Most developed countries do not recommend PCV in adults, believing that with the high coverage in the infant programme, adult disease will (eventually) decline. The US vaccine de
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Streptomycin sulfate br Material and methods br Results br
2019-06-24
Material and methods Results Discussion ES-SCLC is a disease with poor prognosis. Treatment outcome has not improved significantly during the last decades despite great efforts have been made. Maintenance therapy has been tried in several clinical trials with the aim to prevent the onset of
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Any abnormality causing a loss
2019-06-21
Any abnormality causing a loss-of-function in the IKs macromolecular complex may lead to adrenergic-induced imbalance in ventricular repolarization currents and consequent QTc prolongation, which is identified based on the defective response of IKs to PKA stimuli due to mutations in KCNQ1 (-G269S, -
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It is important to know whether pilsicainide
2019-06-21
It is important to know whether pilsicainide can be used as a therapeutic agent for LQT2 patients; and if so, we should determine the types of LQT2 mutation carriers to whom pilsicainide could be administered. As shown in Fig. 8, we examined the effects of pilsicainide on two mutant hERG proteins, G
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La ignorancia que evidencia Xa Am rica po tica respecto
2019-06-21
La ignorancia que evidencia Xa. América poética respecto de los literatos mexicanos corrobora la falta de proximidad entre zonas tan distantes del orbe hispanoamericano. Al mismo tiempo comprueba el vacío biográfico que en este punto muestran las revistas mexicanas o, más exactamente, El Recreo de l
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Modelling studies have estimated that the implementation of
2019-06-21
Modelling studies have estimated that the implementation of Xpert MTB/RIF, either in addition to or as a replacement to smear microscopy, will be cost-effective for the diagnosis of tuberculosis and mutidrug-resistant (MDR) tuberculosis in countries with a high burden. The incremental cost of each d
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br INTRODUCCI N La historia
2019-06-21
INTRODUCCIÓN La historia política de Colombia se ha desarrollado en una tensión permanente. Como lo plantea Cárdenas, esta tensión siempre ha surgido entre la guerra y la búsqueda de la paz. Según el autor: “desde el mismo origen del Estado colombiano, la violencia y los conflictos han sido un el
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br Drug resistance In clinical practice there is
2019-06-21
Drug resistance In clinical practice, there is no cross–drug-resistance between As2O3 and RA or other antileukemic agents. This may be explained by the non-liposoluble nature of As2O3, its small molecular weight, and its distinctive modes of action [20]. In our observation, primary As2O3 resistan
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br Conclusion Accumulating clinical data suggest the presenc
2019-06-21
Conclusion Accumulating clinical data suggest the presence of a genetic component in the pathogenesis of AF. In addition to the gene mutations identified in familial AF, the candidate gene approach and GWAS identified genetic risks in the non-familial form of AF. In multiple Western populations,
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In our case the LV triggered pace algorithm had modes
2019-06-21
In our case, the LV-triggered pace algorithm had 2 modes: “RVs” and “RVs+RVEs”. In the “RVs” mode, LV pacing synchronizes with RV-sensed events. It aims to maintain the CRT benefits even if intrinsic AV conduction shortens with an increase in sympathetic nerve activity. In the “RVs+RVEs” mode, LV pa
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The results described thus far suggest
2019-06-21
The results described thus far suggest that PtAF-induced atrial remodeling combined with acute atrial stretch facilitates anchoring of 3-D scroll waves to the border of atrial pectinate muscle and prolongs their life span in favor of AF maintenance. However, why is it that scroll waves anchor to the
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This is similar to the z score with
2019-06-21
This is similar to the z score, with the mean intra-sample correlation providing a “population mean”. A score greater than −1 was considered a good match (1 point), a score greater than −2 was a partial match (0.5 points), and a score less than −2 was no match (0 points). Spatial resolution was then
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