• For example glutamate is increasingly recognized as one of t

  2019-05-05

  

  For example, glutamate is increasingly recognized as one of the important dysregulated signaling molecules in cancer biology, especially in the context of bone metastasis. Commonly recognized as an excitatory neurotransmitter necessary for normal jnk inhibitors function, glutamate is also intimatel

• LQT can have numerous clinical

  2019-05-05

  

  LQT1 can have numerous clinical manifestations, ranging from no symptoms to sudden cardiac death, which reflects the heterogeneity in channel dysfunction. Mutation type, location, and even a patient׳s ethnic background, age, and gender are critical factors that affect the pathophysiology of the dise

• The patient was consented to treatment on

  2019-05-05

  

  The patient was consented to treatment on clinical trial NCT02527447 and received treatment with salvage chemotherapy of mitoxantrone 12mg/m2/day IV on days 1–3, etoposide 200mg/m2/day continuous IV infusion (CIV) on days 8–10, and cytarabine 500mg/m2/day CIV on days 1–3 and 8–10 (EMA). Infectious p

• br Method br Results br Discussion The present

  2019-05-04

  

  Method Results Discussion The present evaluation of ΔFCL in chronic AF patients over a long-term observation BTL105 revealed a few interesting findings. First, at the end of the 6-year observation period, the mean FCL had prolonged from 154±20ms to 187±37ms in patients with ARB therapy (p=

• br Ethics br Funding br

  2019-05-04

  

  Ethics Funding Conflicts of interest Acknowledgments Case A 68-year-old man with palpitations was referred to our center for catheter ablation because of drug-refractory atrial fibrillation (AF). The preoperative multidetector computed tomography showed a congenital vascular anomaly:

• Introduction The heart beat provides the mechanical

  2019-05-04

  

  Introduction The heart beat provides the mechanical force for the pumping of oxygenated blood to, and deoxygenated blood away from, the peripheral tissues [1]. This depends critically on the orderly activation and recovery of electrical excitation through the myocardium. Disruptions of this can lea

• Es de todos conocido que durante el reinado de Felipe

  2019-05-04

  

  Es de todos conocido que durante el reinado de Felipe III y su privado, el duque de Lerma, la corrupción, el cohecho y la venta de cargos alcanzaron niveles inusitados. El desplome de la legalidad se sumó purchase Sephin 1 la crisis económica que venía arrastrándose desde el reinado de Felipe II. En

• Ante la falta de un ambiente estimulante para la producci

  2019-05-04

  

  Ante la falta de un ambiente estimulante para la producción de un pensamiento crítico y una conciencia social, Pablo Molinet (1975) escribe: “Quizá nuestra época nos dejó hablando solos” (93). No es de extrañar: luego de 1968, las concentraciones de jóvenes fueron vistas como un peligro y se dispuso

• br es resultado de una larga investigaci

  2019-05-04

  

  es resultado de una larga investigación de la obra de Juan Rulfo, pero es asimismo el fruto de largas reflexiones sobre “el arte de narrar” en general y sobre las relaciones que la literatura entabla con la cultura y la historia en que se inscribe, conexiones ellas mismas históricas. Desde el artí

• No que concerne ao territ rio partimos do princ pio

  2019-05-04

  

  No que concerne ao território, partimos do princípio de que os traços culturais de um grupo humano são inseparáveis de suas estruturas espaciais, sendo estriol apreensão do espaço crucial para que os grupos étnicos construam e comuniquem suas identidades e diferenças. Para ElHajji, o desejo de disti

• Acute kidney injury is a common

  2019-05-04

  

  Acute kidney injury is a common disorder worldwide, occurring in more than 13 million people every year, 85% of whom live in low-income or middle-income countries (LMICs). The disease imposes a severe burden of morbidity and mortality, with a major economic effect on health-care expenditure worldwid

• Furthermore many potential risk factors

  2019-05-04

  

  Furthermore, many potential risk factors were examined in the current study, which contained a broad array of factors. Based on such a classification, groups of some factors were earlier referenced in the literature. Although the distribution of association between some risk factors and SRH were sim

• Introduction Researchers have long followed the

  2019-04-30

  

  Introduction Researchers have long followed the strategy that in order to achieve a fuller understanding of the causes of disease and how they can be prevented, it is necessary to study the biochemical and physiological processes involved in the etiology of disease. As I have argued in previous pap

• One of the lessons the global health

  2019-04-30

  

  One of the lessons the global health what does the cytoskeleton do learned from its experience with HIV was the need to rapidly identify individuals who are eligible for treatment. Yet HCV is severely underdiagnosed ( Lancet Glob Health —The following sentence should have read “Alarmingly, almost

• br Methods br Results A total

  2019-04-30

  

  Methods Results A total of 2136 cases, including 614 controls, and 707 LAA, 375 SVO, and 440 HICH cases, were enrolled in this study. Clinical parameters between the control individuals and patients with different stroke subtypes are listed in Table 1. The average age and serum HDL-C level wer

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