• br Future directions There is increasing evidence

  2019-05-18

  

  Future directions There is increasing evidence that osteoblasts are important components of the bone metastatic niche, but their precise contribution in supporting tumour cell engraftment, dormancy and survival remains to be defined. Unlike osteoclasts, the role of osteoblasts in bone metastasis

• br Erythropoietin and the HSC niche Many molecules produced

  2019-05-18

  

  Erythropoietin and the HSC niche Many molecules produced both locally and systemically, including erythropoietin (Epo) and adrenergic catecholamines, also appear to affect HSC niche and metastatic lesions in the bone marrow. EPO is a hematopoietic hormone produced predominantly in the kidneys in

• Therefore the patient was diagnosed

  2019-05-18

  

  Therefore, the patient was diagnosed with BIP, and steroid therapy with oral prednisolone at 40mg/day (0.5mg/kg/day) was initiated. The patient responded well to steroid therapy. After several weeks, his respiratory condition improved to Hugh–Jones class I. Since the imaging findings improved and th

• br Conflict of interest br Acknowledgments br

  2019-05-18

  

  Conflict of interest Acknowledgments Introduction Electroanatomical mapping is useful for locating a possible reentrant circuit, but it has limitations in terms of analyzing the functional property of the circuit [1,2]. Entrainment mapping using the postpacing interval (PPI) and the activat

• Sin considerar la poes a

  2019-05-18

  

  Sin considerar la poesía de Villaurrutia en esta ocasión, es evidente que el pasaje citado representa una elocuente cristalización del su relevancia para el pensamiento y la poética de Octavio Paz. Es notable que el juicio crítico de Paz incluya referencias al universo —donde los opuestos coexisten

• br La profesionalizaci n del poeta como un perfil creador

  2019-05-18

  

  La profesionalización del poeta como un perfil creador La oferta sin precedentes que se ha experimentado en el terreno poético luego de varias iniciativas editoriales públicas y privadas en los años 1980-2010 (por ejemplo, Gabriel Bernal Granados o León Plascencia Ñol: 235) ha generado una bonanz

• Vaccines for rotavirus and cholera the

  2019-05-18

  

  Vaccines for rotavirus and cholera—the two diseases with the highest child mortality rates and a significant fraction of the global diarrhoeal burden—are at preliminary stages of implementation. The use of vaccination as a global primary-prevention strategy can also be rapidly strengthened with the

• Competing pressures for resources across sectors however mea

  2019-05-18

  

  Competing pressures for resources across sectors, however, mean that increasing the proportion of resources for health will be difficult. Efficiency gains in the health sector could help to make the case for more investment. Countries need to tackle major sources of inefficiency by doing more of the

• br Conclusion br Funding br Conflict of

  2019-05-17

  

  Conclusion Funding Conflict of interest Introduction Over the last decade, the unabated increase in the number of transseptal catheterizations has been related to an increase in atrial fibrillation (AF) ablation procedures. Transseptal puncture (TP) is usually safe in experienced hands [

• Pero m s all del

  2019-05-17

  

  Pero más allá del folclore, la conmemoración, con su ampulosidad y minucia, debía servir para medir la destreza virtuosa de los participantes, al exigir cierta competencia en la observancia de sus enigmas por parte de nuevos cristianos “ya bien enseñados en la Fe” (nos dice también Ávila) tras haber

• br El hispanismo criollo de vasconcelos br Conclusiones pr s

  2019-05-17

  

  El hispanismo criollo de vasconcelos Conclusiones: “próspero” vasconcelos Sin la disciplina personal ni el pragmatismo, inculcado por la pequeña escuela texana, Vasconcelos no hubiera logrado todo lo que se propuso desde joven. El peligro de la dispersión y la pereza latinoamericana ya lo habí

• br Conflict of interest br Introduction

  2019-05-17

  

  Conflict of interest Introduction Hepatosplenic T cell lymphoma (HSTCL) is a very rare type of hematologic malignancy, making up about 5% of peripheral T-cell lymphomas. It predominantly affects young male adults, with a higher incidence in patients submitted to immunosuppressive treatment for

• The deletion of q seen in our patient included the

  2019-05-17

  

  The deletion of 14q seen in our patient included the IGH locus at 14q32.33. This is noteworthy, because loss of 14q has been reported as a recurrent aberration acquired during the natural history of CLL. The acquisition of a del(14) may thus be indicative of CLL in transformation. In a study of a la

• proton pump inhibitor Advani et al reported that CsA

  2019-05-17

  

  Advani et al. reported that CsA was associated with good overall and durable responses. Although the mechanism remains unclear, CsA may inhibit the function of T cells, including their production of cytokines involved in the progression of AITL. Consequently, immunosuppressive therapies might exacer

• br Conclusions br Disclosures br Introduction

  2019-05-17

  

  Conclusions Disclosures Introduction Since their introduction, at the end of fifties, cardiovascular implantable devices (CIEDs) have widely expanded in number and in their functions [1,2]. The dramatic increase in the number of CIEDs implanted in the last decade is mainly due to the aging

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